Biographies

Edward W. Holmes, M.D

Dr. Holmes received a Doctor of Medicine degree from the University of Pennsylvania in 1967 and then pursued internal medicine training at the Hospital of the University of Pennsylvania and Duke University Medical Center. He joined the faculty at Duke University School of Medicine and was also appointed a Howard Hughes Medical Investigator in 1974. After serving as the Chief of Endocrinology, Metabolism, and Genetics, and holding the James B. Wyngaarden Professorship of Medicine at Duke University, he was recruited to the University of Pennsylvania School of Medicine in 1991 to become the Chair of the Department of Medicine and the Frank Wister Thomas Professor of Medicine and Genetics. In 1997 he moved to Stanford University School of Medicine to become the Joseph Grant Professor in the School of Medicine, the Senior Associate Dean for Research, Vice President of Translational Medicine and Clinical Research, and Special Counselor to the President of the University on Biomedical Research. In January 1999, Dr. Holmes returned to Duke University as the Dean of the School of Medicine and Walter Kempner Professor in Medicine and Genetics. Dr. Holmes was appointed Vice Chancellor for Health Sciences and Dean of the School of Medicine at the University of California, San Diego in the fall of 2000.

Dr. Holmes engaged in basic biomedical and clinical research throughout his academic career, holding continuous NIH funding from 1975 through 2000, including a MERIT Award. His laboratory has focused on the molecular bases of human disease. After cloning the first member of the AMP deaminase multigene family, his group pioneered a multinational effort to define the role of these genes in health and disease.

Dr. Holmes has been a national leader in developing innovative programs for training and sustaining physician scientists in academic medical centers. He has served on numerous university, industrial and national advisory boards. He currently serves on the Research and Discovery Advisory Board of GlaxoSmithKline, and the Board of Directors of Tularik, Inc. He has been elected to membership in the American Society for Clinical Investigation, the Association of American Physicians, a Fellow of the American Association for the Advancement of Science, and a member of the Institute of Medicine of the National Academy of Sciences.

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